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Extracting skin properties from diseased skin using a modified stratified model

Mr. Jacob Young1, Ms. Xuefei Ding1, Prof. Joesph Hardwick2, Dr. Arturo Hernandez-serrano1, Mr. Benjamin Page1, Prof. Emma Pickwell-MacPherson1
1University of warwick, Coventry, United Kingdom. 2Institute of Applied and Translational Technologies in Surgery, Coventry, United Kingdom

Abstract

In this work we will demonstrate that the stratified medium theory model [1,2] can be used to model the THz reflection [3] of both dry skin conditions, and complicated areas of skin such as the palm (which has a thick layer on the outside) [4]. This modelling can be used together with other techniques, such as spectrogram analysis, to show the location of boundaries in the skin: allowing diseased regions inside the skin to be recognized. 

 

Using data from a clinical study of in vivo THz imaging conducted with the University Hospital of Coventry and Warwickshire, we apply these methods to measurements of both healthy skin and diseased skin from a variety of areas of the body. We show their dynamic hydration profiles and break down some of the distinctions between healthy and dry skin.


 [1] Bennett D, et al. “Stratified media model for THz reflectometry of the skin”. IEEE Sensors Journal. (5), 11 (2011).                                              [2] X Ding, et al. “Retrieving the dynamic hydration profile of skin in vivo with a handheld THz probe”. IRMMW-THz 2023.                                      [3] H Lindley-Hatcher, et al. “A robust protocol for in vivo THz skin measurements”. J. Infrared Millim. Terahertz Waves, (9), 40 (2019).                    [4] M Egawa. “Raman microscopy for skin evaluation”. Analyst RSC. (146), 1142  (2021).